Faslodex

उत्पाद अवलोकन

About Faslodex

Faslodex is an anti-oestrogen medicine used to treat advanced or metastatic breast cancer in the following patients.

What it is used for

Faslodex is used to treat postmenopausal women with a type of breast cancer known as ‘oestrogen-receptor positive cancer’ who have not previously had hormonal treatment, or whose cancer had come back after treatment with another anti-oestrogen. It is also used in women with a type of breast cancer known as ‘HR-positive, HER-2 negative cancer’ who have previously had hormonal treatment. In women with this type of breast cancer, Faslodex is used in combination with palbociclib.

How it is used

Faslodex is available as a solution for injection in prefilled syringes (250 mg). The recommended dose is 500 mg given once a month, with an additional 500-mg dose two weeks after the first dose. The dose is given as two injections, each given into the muscle of one buttock over one to two minutes. Faslodex can only be obtained with a prescription.

How it works

Most types of breast cancer are stimulated to grow when the hormone oestrogen attaches to targets (receptors) on cancer cells. The active substance in Faslodex, fulvestrant, is an anti-oestrogen. It blocks the receptors for oestrogen on cells and causes the number of oestrogen receptors to fall. As a result, the cancer cells are not stimulated to grow by oestrogen and this slows down the growth of the tumour.

Active substance: fulvestrant

Source: EMA EPAR