Cinryze
Analogs of Cinryze
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ਸਰਗਰਮ ਤੱਤ: C1 inhibitor (human)
ਉਤਪਾਦ ਝਲਕ
About Cinryze
Cinryze is a powder and solvent that are made up into a solution for injection. It contains the active substance C1 inhibitor (human).
What it is used for
Cinryze is used to treat angioedema (swelling) attacks in adults and adolescents aged 12 to 17 years with hereditary angioedema. Patients with hereditary angioedema have attacks of swelling that can occur anywhere in the body, such as in the face or limbs, or around the gut, causing discomfort and pain. Cinryze is also used for the prevention of angioedema attacks that can be triggered by medical, dental or surgical procedures. Cinryze is also used for routine prevention in patients who have severe and frequent angioedema attacks for which prevention with oral medicines is not adequate or in patients whose attacks are not adequately treated. The medicine can only be obtained with a prescription.
How it is used
Treatment with Cinryze should be started under the supervision of a doctor experienced in treating hereditary angioedema. Cinryze is given as an injection into a vein. For treatment of angioedema attacks, the patient is given 1,000 Units at the first sign of an angioedema attack. A second dose of 1,000 Units may be given if the patient has not responded adequately after one hour, or sooner for attacks in the larynx (voice box) or if the start of the treatment had been delayed. For routine prevention, Cinryze is given as 1,000 units every three or four days. The doctor should review the need for routine prevention on a regular basis and can adjust the frequency of the injections according to how the patient is responding. For prevention before a medical, dental or surgical procedure, Cinryze is given as 1,000 units within the 24 hours before the procedure. The doctor may decide that the caregivers and patients can carry out the injection provided that they have been adequately trained.
How it works
The active substance in Cinryze, human C1 inhibitor, is a protein extracted from human blood. The C1 inhibitor protein is required to control the ‘complement’ and ‘contact’ systems, collections of proteins in the blood that fight against infection and cause inflammation. Patients with low levels of this protein have excessive activity of these two systems, which leads to the symptoms of angioedema. Cinryze is used to replace the missing C1 inhibitor, correcting the deficiency and helping to prevent or treat angioedema attacks.
Active substance: C1 inhibitor (human)
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