Riluzole Zentiva
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Active Ingredient: riluzole
Product Overview
About Riluzole Zentiva
Riluzole Zentiva is a medicine containing the active substance riluzole. It is available as tablets (50 mg). This medicine is the same as Rilutek, which is already authorised in the European Union (EU). The company that makes Rilutek has agreed that its scientific data can be used for Riluzole Zentiva (‘informed consent’).
What it is used for
Riluzole Zentiva is used in patients with amyotrophic lateral sclerosis (ALS). ALS is a form of motor-neurone disease where attacks of the nerve cells responsible for sending instructions to the muscles lead to weakness, muscle waste and paralysis. Riluzole Zentiva is used to extend the patient’s life, or the time before they need to use mechanical ventilation. Riluzole Zentiva should not be used in patients with any other form of motor-neurone disease. The medicine can only be obtained with a prescription.
How it is used
Treatment with Riluzole Zentiva should only be started by a specialist doctor with experience in the management of motor neurone diseases. In adult and elderly patients, it is given as 100 mg a day (50 mg every 12 hours). For more information please see the package leaflet.
How it works
The active substance in Riluzole Zentiva, riluzole, acts on the nervous system. The exact way in which it works in ALS is not known. It is thought that the destruction of nerve cells in motor-neurone disease may be caused by too much glutamate, a neurotransmitter (chemical messenger). Riluzole stops the release of glutamate and this may help in preventing the nerve cells being damaged.
Active substance: riluzole
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