Nexviadyme
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Active Ingredient: avalglucosidase alfa
Product Overview
About Nexviadyme
Nexviadyme is a treatment for Pompe disease or other inherited diseases of the same type.
What it is used for
Nexviadyme is used to treat Pompe disease or other inherited diseases of the same type.
How it is used
Nexviadyme treatment should be supervised by a doctor who has experience managing patients with Pompe disease or other inherited diseases of the same type. Nexviadyme is given as an infusion (drip) into a vein once every two weeks, and the dose depends on the patient’s body weight. A doctor may decide to increase the dose for patients with infantile-onset Pompe disease (Pompe disease that appears at an early age) who do not improve with the regular dose. Patients who have no major side effects with the first few infusions may be able to have their infusions given at home.
How it works
The active substance in Nexviadyme, avalglucosidase alfa, is a version of the enzyme alpha-glucosidase, which is lacking in people with Pompe disease. Alpha-glucosidase breaks down glycogen into glucose that can be used for energy by the body’s cells. If the enzyme is not present, glycogen builds up in certain tissues, including the heart and diaphragm (the main breathing muscle under the lungs), causing damage to them. By replacing the missing enzyme, avalglucosidase alfa helps break down glycogen and stop it from building up and causing the symptoms of the condition.
Active substance: avalglucosidase alfa
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