Aubagio
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Active Ingredient: teriflunomide
Product Overview
About Aubagio
Aubagio is a medicine that contains the active substance teriflunomide.
What it is used for
Aubagio is used to treat patients from the age of 10 years with multiple sclerosis (MS), a disease in which inflammation destroys the protective sheath around the nerves. It is used in the type of MS known as relapsing-remitting MS, when the patient has flare-ups of symptoms (relapses) followed by periods of recovery (remissions).
How it is used
Aubagio can only be obtained with a prescription and treatment should be started and supervised by a doctor who has experience in the management of MS. Aubagio is available as tablets. The recommended dose for adults is 14 mg once a day. The dose for children depends on their body weight.
How it works
In MS, the body’s immune system malfunctions and attacks parts of the central nervous system (the brain and spinal cord), causing the inflammation that damages the nerve sheaths. The active substance in Aubagio, teriflunomide, blocks an enzyme called ‘dihydro-orotate dehydrogenase’ which is necessary for cells to multiply. The exact way teriflunomide works in MS is not known but it is thought to reduce the number of lymphocytes which form part of the immune system and are involved in the inflammation process. With fewer lymphocytes, there is less inflammation, helping to control the symptoms of MS.
Active substance: teriflunomide
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