ОНКАСПАР

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About ОНКАСПАР

ОНКАСПАР is a medication used in the treatment of acute lymphoblastic leukemia (ALL) in patients who have developed or are at high risk of developing asparaginase-associated antithrombin deficiency. It contains the active ingredient Pegaspargase, a recombinant form of the enzyme L-asparaginase.

Key Benefits & Uses

• Treatment of acute lymphoblastic leukemia (ALL) in patients who have developed or are at high risk of developing asparaginase-associated antithrombin deficiency.
• Used in combination with other chemotherapy medications to treat ALL.
• May be used in patients who have developed hypersensitivity to E. coli-derived asparaginase.

Active Ingredient & Action

Pegaspargase works by depleting the amino acid asparagine, which is essential for the growth and survival of lymphoblasts. By inhibiting asparagine synthesis, Pegaspargase exerts its antineoplastic effect, ultimately leading to the death of rapidly dividing lymphoblasts.

Important Notes

ОНКАСПАР should be administered under the guidance of a healthcare professional. Patients with a history of pancreatitis or other conditions that may increase the risk of pancreatitis should be closely monitored. Common side effects include pancreatitis, allergic reactions, and thrombosis. It is essential to follow the recommended dosage and administration schedule to minimize the risk of adverse effects.