Entacapone Orion
Аналоги Entacapone Orion
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Активный ингредиент: entacapone
Описание товара
About Entacapone Orion
Entacapone Orion is a medicine that contains the active substance entacapone. It is available as tablets (200 mg). This medicine is the same as Comtess, which is already authorised in the European Union (EU). The company that makes Comtess has agreed that its scientific data can be used for Entacapone Orion (‘informed consent’).
What it is used for
Entacapone Orion is used to treat patients with Parkinson’s disease. Parkinson’s disease is a progressive brain disorder that causes shaking, slow movement and muscle stiffness. Entacapone Orion is used together with levodopa (either a combination of levodopa and benserazide or a combination of levodopa and carbidopa) when the patient is having ‘fluctuations’ towards the end of the period between two doses of their medication.
How it is used
Entacapone Orion is only used in combination either with levodopa and benserazide or with levodopa and carbidopa. It is taken as one tablet with each dose of the other medicine, up to a maximum of 10 tablets a day. It can be taken with or without food. When patients first add Entacapone Orion to their existing medication, they may need to take a lower daily dose of levodopa, either by changing how often they take it, or by reducing the amount of levodopa taken in each dose.
How it works
In patients with Parkinson’s disease, the cells in the brain that produce the neurotransmitter dopamine begin to die and the amount of dopamine in the brain decreases. The active substance in Entacapone Orion, entacapone, works to restore the levels of dopamine in the parts of the brain that control movement and coordination. It only works when it is taken with levodopa, a copy of the neurotransmitter dopamine that can be taken by mouth. Entacapone blocks an enzyme that is involved in the breakdown of levodopa in the body called catechol-O-methyl transferase (COMT). As a result, levodopa remains active for longer.
Active substance: entacapone
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