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Ixiaro
medicine 📍 EU

Ixiaro

Аналоги Ixiaro

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Ингредиенты

Активный ингредиент: Japanese-encephalitis virus, inactivated (attenuated strain SA14-14-2 grown in vero cells)


Описание товара

About Ixiaro

Ixiaro can only be obtained with a prescription.

How it is used

Ixiaro is given by injection into a muscle, preferably into the shoulder muscle, or into the thigh muscle in young children. In adults, including those aged above 65 years, and children aged 3 years and older, a full dose of Ixiaro (0.5 ml) should be given, and an additional 0.5 ml dose should be given four weeks later. Adults from 18 to 65 years can also receive a rapid vaccination course, where the second dose is given seven days after the first dose. In children aged between 2 months and 3 years, half the adult dose of Ixiaro (0.25 ml) should be given, and an additional 0.25 ml dose should be given four weeks later. It is recommended that individuals who receive the first dose of Ixiaro should receive both doses. The second dose should be given at least one week before potential exposure to the virus. In adults, the second dose can be given up to 11 months after the first. Adults from 18-65 years who are likely to be exposed to the Japanese encephalitis virus again or who are at continuous risk of the disease should receive a booster dose of Ixiaro one to two years later and a second booster dose 10 years after the first booster. Children and adolescents may also receive a booster dose one to two years after the initial vaccination. A booster dose should also be considered for adults aged above 65 years before any further exposure to the Japanese encephalitis virus. Ixiaro can be injected under the skin in people who have a bleeding disorder such as low blood platelet counts or haemophilia.

How it works

Vaccines work by ‘teaching’ the immune system (the body’s natural defences) how to defend against a disease. Ixiaro contains small amounts of the virus that causes Japanese encephalitis, which has been inactivated (killed) so that it cannot cause the disease. When a person is given the vaccine, the immune system identifies the inactivated virus as ‘foreign’ and makes antibodies against it. In future, the immune system will be able to produce antibodies quickly and in large numbers when it is exposed to Japanese encephalitis virus again. The antibodies will help to protect against the disease. The vaccine is ‘adsorbed’. This means that the virus is fixed onto aluminium compounds, to stimulate a better response. The virus in Ixiaro is grown in mammal cells (‘Vero cells’) under laboratory conditions.

Active substance: Not specified

Source: EMA EPAR

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