COLISTIMETHATE FOR INJECTION U.S.P.
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Active Ingredient: COLISTIN (COLISTIMETHATE SODIUM)
Product Overview
About COLISTIMETHATE FOR INJECTION U.S.P.
COLISTIMETHATE FOR INJECTION U.S.P. is a prescription medication containing the active ingredient COLISTIN (COLISTIMETHATE SODIUM), a polymyxin antibiotic used to treat severe bacterial infections. It is administered via injection and is available in a sterile solution form.
Key Benefits & Uses
- Treatment of complicated urinary tract infections (UTIs) caused by susceptible strains of Pseudomonas aeruginosa.
- Treatment of infections caused by susceptible strains of Pseudomonas aeruginosa, including pneumonia, septicemia, and infections of the skin and soft tissues.
- Adjunctive therapy for the treatment of infections caused by susceptible strains of Acinetobacter species, including A. baumannii.
Active Ingredient & Action
COLISTIN (COLISTIMETHATE SODIUM) works by binding to the lipopolysaccharide (LPS) component of the bacterial cell wall, disrupting the bacterial membrane and ultimately leading to bacterial cell death. This mechanism of action makes COLISTIN effective against a wide range of Gram-negative bacteria, including Pseudomonas aeruginosa and Acinetobacter species.
Important Notes
COLISTIMETHATE FOR INJECTION U.S.P. should only be used under the guidance of a qualified healthcare professional. Patients with renal impairment or those receiving concomitant nephrotoxic agents should be closely monitored for signs of nephrotoxicity. The solution should be administered slowly over a period of 3-5 minutes to minimize the risk of infusion-related reactions.
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