Tuznue
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Active Ingredient: trastuzumab
Product Overview
About Tuznue
Tuznue was intended for use in adults, alone or in combination with other cancer medicines, to treat early breast cancer and metastatic breast cancer (that has spread to other parts of the body). It was also intended to be used together with other cancer medicines to treat gastric (stomach) cancer that has spread to other parts of the body.
What it is used for
Tuznue was intended for use in patients with HER2-positive cancer, meaning that the cancer produces a protein called human epidermal growth factor receptor 2 (HER2) in large quantities on the surface of the tumour cells, which makes the tumour cells grow more quickly.
How it is used
Tuznue contains the active substance trastuzumab and was to be available as a powder to be made into a solution for infusion (drip) into a vein.
How it works
Tuznue was expected to work in the same way as the reference medicine, Herceptin. The active substance in Tuznue, trastuzumab, is a monoclonal antibody (a type of protein that attaches to a target on cells in the body). Trastuzumab is designed to recognise and attach to the HER2 protein. By attaching to HER2, trastuzumab activates cells of the immune system, which then kill the tumour cells. Trastuzumab also stops HER2 from producing signals that cause the tumour cells to grow.
Active substance: trastuzumab
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