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Zomarist
medicine 📍 EU

Zomarist

Analogs of Zomarist

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Ingredients

Active Ingredient: vildagliptin;metformin hydrochloride


Product Overview

About Zomarist

Zomarist is a medication used to treat type 2 diabetes.

What it is used for

Type 2 diabetes is a disease in which the pancreas does not make enough insulin to control the glucose level in the blood or the body is unable to use insulin effectively.

How it is used

Zomarist is available as tablets (50 mg/850 mg and 50 mg/1,000 mg) and the recommended dose is one tablet twice a day (one in the morning and one in the evening). The starting tablet strength depends on the patient’s current treatment and the expected effects of Zomarist. Taking Zomarist with or just after food may reduce any stomach problems caused by metformin. The doctor should carry out tests to check the patient’s kidney and liver function before treatment with Zomarist and at regular intervals during treatment. The medicine can only be obtained with a prescription.

How it works

Zomarist contains two active substances, each with a different mode of action. Vildagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that works by blocking the breakdown of incretin hormones in the body. These hormones are released after a meal and stimulate the pancreas to produce insulin. By blocking the breakdown of incretin hormones in the blood, vildagliptin prolongs their action, stimulating the pancreas to produce more insulin when blood glucose levels are high. Vildagliptin does not work when the blood glucose is low. Vildagliptin also reduces the amount of glucose made by the liver by increasing insulin levels and decreasing the levels of the hormone glucagon. Metformin works mainly by inhibiting glucose production and reducing its absorption in the gut. As a result of the action of both substances, the blood glucose is reduced, which helps to control type 2 diabetes.

Active substance: vildagliptinmetformin

Source: EMA EPAR

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