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Glyxambi
medicine 📍 EU

Glyxambi

Analogs of Glyxambi

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Ingredients

Active Ingredient: empagliflozin;linagliptin


Product Overview

About Glyxambi

Glyxambi is a diabetes medicine used in adults with type 2 diabetes to improve control of their blood glucose (sugar) levels.

What it is used for

Glyxambi is used in the following groups:

  • patients whose blood glucose levels are not controlled well enough by a combination of one of Glyxambi’s active substances (empagliflozin or linagliptin) with other diabetes medicines (metformin and/or a sulphonylurea);
  • patients who are already taking empagliflozin and linagliptin as separate tablets.

How it is used

Glyxambi is available as tablets containing 10 or 25 mg of empagliflozin with 5 mg of linagliptin, and can only be obtained with a prescription. The recommended dose is one tablet once a day.

Patients switching from empagliflozin and linagliptin to Glyxambi should receive the strength of Glyxambi that corresponds to the doses of empagliflozin and linagliptin in the separate tablets they were taking.

If Glyxambi is used in combination with insulin or a sulphonylurea, their doses may need to be reduced to decrease the risk of hypoglycaemia (low blood sugar levels).

The doctor may need to reduce the dose of Glyxambi or discontinue its use in patients with reduced kidney function.

How it works

Type 2 diabetes is a disease in which the body does not make enough insulin to control the level of glucose in the blood or when the body is unable to use insulin effectively.

The two active substances in Glyxambi work in different ways to lower glucose levels:

  • Empagliflozin works by blocking a protein in the kidneys called sodium-glucose co-transporter 2 (SGLT2).
  • Linagliptin is a dipeptidyl-peptidase-4 (DPP-4) inhibitor, which works by blocking the breakdown of incretin hormones in the body.

Active substance: empagliflozin and linagliptin

Source: EMA EPAR

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