ЗОЛТЕРО
Analogs of ЗОЛТЕРО
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Active Ingredient: Zoledronic acid
Product Overview
About ЗОЛТЕРО
ЗОЛТЕРО is a medication containing the active ingredient Zoledronic acid, a bisphosphonate used in the treatment of bone diseases. It is a sterile, clear, colorless solution for intravenous administration.
Key Benefits & Uses
- Treatment of hypercalcemia of malignancy, including hypercalcemia associated with bone metastases, multiple myeloma, and other malignancies.
- Prevention of skeletal fractures in patients with bone metastases from solid tumors.
- Treatment of bone metastases in patients with breast cancer, multiple myeloma, or other malignancies.
Active Ingredient & Action
Zoledronic acid works by inhibiting osteoclast-mediated bone resorption, thereby reducing bone turnover and increasing bone density. It binds to hydroxyapatite in bone, forming a stable, non-dissociable complex that interferes with the mevalonate pathway, leading to the inhibition of osteoclast function and bone resorption.
Important Notes
ЗОЛТЕРО should be administered under the supervision of a healthcare professional. It is essential to follow the recommended dosing schedule and to monitor patients for signs of renal impairment, hypocalcemia, and other potential side effects. Patients with creatinine clearance < 35 mL/min should not receive ЗОЛТЕРО.
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