Mycamine

ਉਤਪਾਦ ਝਲਕ

About Mycamine

Mycamine is a powder that is dissolved to make a solution for infusion (drip into a vein). It contains the active substance micafungin.

What it is used for

Mycamine is used in babies, children and adults in the following situations: to treat invasive candidiasis (a type of fungal infection caused by a yeast-like fungus called Candida). ‘Invasive’ means that the fungus has spread into tissue and blood vessels; to prevent infection with Candida in patients who are having a bone-marrow transplant or who are expected to have neutropenia (low levels of neutrophils, a type of white blood cell) for 10 days or more. Mycamine is also used to treat candidiasis in the oesophagus (gullet) in patients over 16 years of age for whom intravenous treatment is suitable. Because of a possible risk of liver tumours, Mycamine is only to be used if other antifungal medicines are not appropriate. The medicine can only be obtained with a prescription.

How it is used

Treatment with Mycamine should be initiated by a doctor who has experience managing fungal infections, and after considering official or national guidance on the use of antifungal medicines. Mycamine is given once a day as an infusion lasting around one hour. The dose depends on what it is being used for, the patient’s weight, and the response to treatment. Patients being treated for invasive candidiasis should receive Mycamine for at least two weeks, and for a week after symptoms have resolved and there are no signs of fungus in the blood. Patients being treated for oesophageal candidiasis should continue to receive Mycamine for at least one week after symptoms have resolved. When Mycamine is used to prevent Candida infection, treatment should continue for one week after white-blood-cell counts have recovered.

How it works

The active substance in Mycamine, micafungin, is an antifungal medicine, which belongs to the group ‘echinocandins’. It works by interfering with the production of an essential component of the fungal cell wall called 1,3 ? D glucan. Fungal cells treated with Mycamine have incomplete or defective cell walls, making them fragile and unable to grow. The list of fungi against which Mycamine is active can be found in the summary of product characteristics (also part of the EPAR).

Active substance: micafungin

Source: EMA EPAR