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About KhARTYL ROZ

KhARTYL ROZ is intended for the treatment of arterial hypertension in adults patients, which have NALEZhNYM ChYNOM KONTROLOVANYI level KROV'IaNOHO pressure during time ODNOChASNOHO use RAMIPRYLU and ROZUVASTATYNU in TYKh ZhE doses, that and in FIKSOVANII combination.

Also medicine is intended for the treatment of primary HIPERKhOLESTERYNEMII, ZMIShANOI DYSLIPIDEMII and HOMOZYHOTNOI SIMEINOI HIPERKhOLESTERYNEMII.

KhARTYL ROZ also is used for prevention ZNAChNYKh SERTsEVO-SUDYNNYKh disorders in patients with VYSOKYM RYZYKOM development PERShOHO VYPADKU SERTsEVO-SUDYNNOHO disorders.

Composition

KhARTYL ROZ consists with two tablets: ODNIIeI, that contains ROZUVASTATYN calcium (equivalent to 10 mg ROZUVASTATYNU), and ODNIIeI, that contains RAMIPRYL.

Excipients: for tablets ROZUVASTATYNU calcium - cellulose SYLIKATYZOVANA microcrystalline, magnesium stearate (E 572), silicon dioxide colloidal anhydrous (E 551); for tablets RAMIPRYLU - cellulose microcrystalline RN 102 FMC, KROSPIDON type V, HIPROMELOZA 2910, 3 SR, sodium STEARYLFUMARAT.

Indications

KhARTYL ROZ is intended for the treatment of arterial hypertension in adults patients, STAN IaKYKh NALEZhNYM ChYNOM KONTROLIuIeTSIa ODNOChASNYM ZASTOSUVANNIaM RAMIPRYLU and ROZUVASTATYNU in TYKh ZhE doses, that and in FIKSOVANII combination.

Also medicine is intended for the treatment of primary HIPERKhOLESTERYNEMII, ZMIShANOI DYSLIPIDEMII and HOMOZYHOTNOI SIMEINOI HIPERKhOLESTERYNEMII.

Pharmacological properties

ROZUVASTATYN acts by inhibition HMH-KOA-REDUKTAZY, enzyme, which OBMEZhUIe ShVYDKIST PERETVORENNIa 3-HIDROKSY-3-METYLHLUTARYL-KOENZYMU A V MEVALONAT, POPEREDNYK KhOLESTERYNU.

RAMIPRYL acts by inhibition enzyme DYPEPTYDYLKARBOKSYPEPTYDAZY I, which KATALIZUIe PERETVORENNIa angiotensin I on ANHIOTENZYN II.

Source: Compendium