ЕВРІСДІ
Analogs of ЕВРІСДІ
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सक्रिय अवयव: risdiplam
उत्पाद अवलोकन
About EVRISDI
EVRISDI – this medicine, that contains AKTYVNU substance RYSDYPLAM. U KOZhNII PLIaShTsI contains 60 mg RYSDYPLAMU, A 1 ml VIDNOVLENOHO solution – 0,75 mg AKTYVNOI substances. Medicine is intended for oral use.
Composition
Active substance: RYSDYPLAM (60 mg in FLAKONI, 0,75 mg in 1 ml solution). DO SKLADU DOPOMIZhNYKh components VKhODIaT mannitol (E 421), IZOMALT (E 953), POLUNYChNYI AROMATYZATOR, KYSLOTA VYNNA, sodium BENZOAT (E 211), POLIETYLENHLIKOL 6000, SAKhARALOZA, ASKORBINOVA KYSLOTA, DYNATRIIu EDETAT DIHIDRAT.
Indications
Medicine is used for treatment 5q‑ASOTsIIOVANOI SPINALNOI M'IaZOVOI ATROFII (SMA) in children and adults PATsIIeNTIV.
Pharmacological properties
RYSDYPLAM corrects SPLAISYNH POPEREDNYKA MRNK HENA SMN2, ZMINIuIuChY VYKLIuChENNIa EKZONU 7 on its VKLIuChENNIa. This increases production FUNKTsIONALNOHO protein SMN, which KOMPENSUIe its DEFITsYT in SMA. DOSLIDZhENNIa POKAZALY, that in TERAPEVTYChNYKh doses medicine not PRODOVZhUIe INTERVAL QTc in healthy DOBROVOLTsIV.
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