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Paxneury
medicine 📍 EU

Paxneury

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Ingredients

Active Ingredient: guanfacine hydrochloride


Product Overview

About Paxneury

Paxneury is a medicine used to treat ADHD.

What it is used for

The way Paxneury works in ADHD is not established.

How it is used

Paxneury treatment must be started by a doctor specialised in childhood or adolescent behavioural problems. Before starting treatment, the doctor should carry out checks to see whether the patient is at risk of side effects of the medicine (particularly sleepiness, effects on heart rate and blood pressure, and weight gain). The dose of Paxneury requires careful adjustments, taking into account side effects and benefits seen in the patient. Weekly monitoring for signs and symptoms of sleepiness and effects on heart rate and blood pressure is required at the start of treatment and the patient should continue to be monitored at least every 3 months for the first year. Six-monthly monitoring is required thereafter, with more frequent monitoring following any dose adjustment. The recommended starting dose for all patients is 1 mg taken by mouth once a day which is increased to a maintenance dose based on body weight according to the patient’s response and tolerability. The medicine can only be obtained with a prescription.

How it works

The way Paxneury works in ADHD is not established. It is thought that the active substance, guanfacine, might influence the way signals are transmitted between cells in areas of the brain called the prefrontal cortex and basal ganglia by attaching to certain receptors that are heavily concentrated in these areas.

Active substance: guanfacine

Source: EMA EPAR

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