Myalepta
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Active Ingredient: Metreleptin
Product Overview
About Myalepta
Myalepta is a medicine used to treat patients with lipodystrophy.
What it is used for
Patients with lipodystrophy have low levels of a human hormone called leptin, which plays a key role in regulating the break-down of fats and sugars in the body. This leads to loss of fat from under the skin and its build-up in places such as the liver and muscles, as well as high levels of fat in the blood. It also results in insulin resistance (when the body is unable to recognise insulin, a hormone that helps regulate blood sugar levels).
How it is used
Myalepta can only be obtained with a prescription and treatment should be started and monitored by a doctor experienced in the diagnosis and management of patients with metabolic disorders. Myalepta is given as a daily injection under the skin of the abdomen (belly), thigh or upper arm, at the same time every day. The recommended daily dose depends on the patient’s bodyweight and is adjusted based on the patient’s response to treatment. Patients or carers can inject the medicine themselves once they have been trained.
How it works
The active substance in Myalepta, metreleptin, is similar to leptin. It replaces leptin and increases fat breakdown in the blood, muscles and liver, thereby correcting some abnormalities in patients with lipodystrophy, including insulin resistance. However, the medicine does not restore fat tissue under the skin.
Active substance: metreleptin
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