Zydelig
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Active Ingredient: Idelalisib
Product Overview
About Zydelig
Zydelig is a prescription medicine that should be prescribed by a doctor experienced in using cancer medicines.
What it is used for
Zydelig is used to treat blood cancers.
How it is used
Zydelig is available as 100 mg and 150 mg tablets. The recommended dose is 150 mg twice a day, and treatment should be continued for as long as the patient improves or remains stable and the side effects are tolerable. If the patient has severe side effects, treatment must be stopped and can be re-started at a lower dose of 100 mg twice a day. All patients treated with Zydelig should also be given preventive medication against the lung infection Pneumocystis jirovecii pneumonia, and this should be continued for up to 6 months after stopping treatment with Zydelig. Patients should also be monitored for infection and have regular blood tests to measure the level of white blood cells. Zydelig should not be started in patients with any generalised infection (infection that has spread with symptoms affecting the whole body, such as fever and chills).
How it works
The active substance in Zydelig, idelalisib, blocks the effects of an enzyme called PI3K-delta. This enzyme plays a role in the growth, migration and survival of white blood cells but is overactive in blood cancers, where it enables the survival of the cancer cells. By targeting this enzyme and blocking its effects, idelalisib causes death of the cancer cells, thereby delaying or stopping the progression of the cancer.
Active substance: idelalisib
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