Kapruvia
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Active Ingredient: difelikefalin
Product Overview
About Kapruvia
Kapruvia is a prescription medicine that should be administered by a healthcare professional with relevant experience.
What it is used for
Kapruvia is used to treat itching associated with chronic kidney disease.
How it is used
Kapruvia is given as an injection into the vein at the end of a haemodialysis procedure. It is given three times per week and the dose depends on the patient’s weight.
How it works
Difelikefalin, the active substance in Kapruvia, binds to kappa opioid receptors on nerves and immune cells involved in controlling itching and inflammation. By binding to these receptors, difelikefalin activates them, reducing inflammation that could lead to itchiness and decreasing the signals that lead to the feeling of itchiness itself.
Active substance: difelikefalin
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