Ezmekly
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Active Ingredient: mirdametinib
Product Overview
About Ezmekly
Ezmekly is a prescription medicine used to treat tumours caused by NF1.
What it is used for
Ezmekly is used to treat tumours caused by NF1.
How it is used
Ezmekly can only be obtained with a prescription and treatment should be started by a doctor who has experience in the diagnosis and treatment of patients with tumours caused by NF1. Ezmekly is available as capsules to be swallowed, or dispersible tablets which can be dispersed in water. It is taken twice a day, 12 hours apart. Patients take the medicine for 3 weeks, then stop for 1 week, and treatment can continue in repeated cycles until the disease gets worse or side effects become unacceptable.
How it works
The active substance in Ezmekly, mirdametinib, is a small molecule which works by blocking a protein called MEK, which helps control how cells grow and survive. In people with NF1, MEK is overactive, leading to the growth of plexiform neurofibromas on nerve cells. By blocking MEK, mirdametinib helps to prevent the growth of these tumours.
Active substance: mirdametinib
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