Darzalex
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Active Ingredient: daratumumab
Product Overview
About Darzalex
Darzalex is a medication that should be used under the guidance of a healthcare professional.
What it is used for
Darzalex is used for multiple myeloma, smouldering multiple myeloma and AL amyloidosis.
How it is used
Darzalex can only be obtained with a prescription and should be given by a healthcare professional. The first dose should be given in a place where resuscitation equipment is available in case of severe allergic reaction (anaphylaxis). For multiple myeloma, smouldering multiple myeloma and AL amyloidosis, Darzalex is given by injection under the skin; for certain uses in multiple myeloma, it is given by infusion (drip) into a vein. How often Darzalex is given depends on the disease, which other medicines are being given and whether patients can have a transplant or not. Treatment usually starts with one dose of Darzalex once a week. Before and after treatment with Darzalex, patients are given medicines to reduce the risk of infusion-related reactions. If the patient has a severe reaction, the doctor may slow down the infusion rate or stop treatment.
How it works
The active substance in Darzalex, daratumumab, is a monoclonal antibody (a type of protein) that has been designed to attach to the protein CD38, which is found in high amounts on abnormal white blood cells in multiple myeloma and AL amyloidosis. By attaching to CD38 on these cells, daratumumab activates the immune system to kill the abnormal white blood cells.
Active substance: daratumumab
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