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Zolsketil pegylated liposomal
medicine 📍 EU

Zolsketil pegylated liposomal

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Ingredients

Active Ingredient: doxorubicin hydrochloride, liposomal


Product Overview

About Zolsketil pegylated liposomal

Zolsketil pegylated liposomal is a cytotoxic medicine that belongs to the group ‘anthracyclines’.

What it is used for

There is no information available on what Zolsketil pegylated liposomal is used for.

How it is used

Zolsketil pegylated liposomal can only be obtained with a prescription. It should only be given under the supervision of a cancer doctor who is specialised in the use of cytotoxic (cell-killing) medicines. It cannot be interchanged with other medicines that contain doxorubicin. Zolsketil pegylated liposomal is given by infusion (drip) into a vein. The dose depends on the condition it is used for and is calculated on the basis of the patient’s weight and height. The doctor may stop treatment or reduce the dose if certain side effects occur or if the patient has liver problems.

How it works

Doxorubicin, the active substance in Zolsketil pegylated liposomal, interferes with the DNA in cancer cells, preventing them from making more copies of DNA. This means that cancer cells cannot divide and eventually die. Zolsketil pegylated liposomal builds up in areas in the body where the blood vessels have an abnormal shape, such as within tumours, where its action is concentrated. Doxorubicin has been available since the 1960s. In Zolsketil pegylated liposomal, it is enclosed in ‘pegylated liposomes’ (tiny fat particles coated with a substance called polyethylene glycol). This slows down removal of the medicine, allowing it to circulate in the blood for longer. It also reduces its effects on healthy tissues and cells, so it is less likely to cause specific side effects.

Active substance: Doxorubicin

Source: EMA EPAR

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