ONDEXXYA

Product Overview

About ONDEXXYA

ONDEXXYA is a prescription medication containing the active ingredient ANDEXANET ALFA. It is used to treat patients with acute ischemic stroke who have received thrombolytic agents. ANDEXANET ALFA is a selective antidote for low molecular weight heparin (LMWH) and direct oral anticoagulants (DOACs), which can increase the risk of bleeding in patients undergoing thrombolysis.

Key Benefits & Uses

• Treatment of acute ischemic stroke in patients who have received thrombolytic agents
• Reduction of the risk of bleeding associated with thrombolytic therapy in patients with acute ischemic stroke
• Antidote for low molecular weight heparin (LMWH) and direct oral anticoagulants (DOACs)

Active Ingredient & Action

ANDEXANET ALFA is a recombinant, humanized, anti-factor Xa antibody fragment that selectively binds to and neutralizes factor Xa in the presence of LMWH or DOACs. This binding action prevents the anticoagulant effects of these medications, thereby reducing the risk of bleeding in patients undergoing thrombolysis.

Important Notes

ONDEXXYA is a prescription medication and should only be used under the guidance of a healthcare professional. Patients should be carefully evaluated for the presence of LMWH or DOACs before receiving ONDEXXYA. The medication should be administered as directed by the prescribing physician, and patients should be closely monitored for signs of bleeding or other adverse effects.