Ozurdex
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Active Ingredient: dexamethasone
Product Overview
About Ozurdex
Ozurdex is a prescription-only medicine that must be administered by an ophthalmologist (eye specialist) with experience in giving intravitreal injections.
What it is used for
Ozurdex is used to treat macular oedema and uveitis.
How it is used
Ozurdex can only be obtained with a prescription and must be given by an ophthalmologist who has experience in giving intravitreal injections. Each implant is in an applicator and contains 700 micrograms of the active substance, dexamethasone. Patients receive one Ozurdex implant at a time, injected directly into the vitreous humour. Further treatments can be given if the patient’s condition improves but then gets worse and if the doctor believes that the patient will benefit from further treatment. Patients whose vision gets better and stays better should not receive any more implants. Patients whose vision is getting worse and is not improved by Ozurdex should also not receive any more implants.
How it works
The active substance in Ozurdex, dexamethasone, belongs to a group of anti-inflammatory medicines known as corticosteroids. It works by entering cells and blocking the production of vascular endothelial growth factor (VEGF) and prostaglandins, substances that are involved in inflammation. Ozurdex implants are injected directly into the vitreous humour of the eye. This ensures that adequate amounts of dexamethasone reach the area inside the eye where the inflammation in macular oedema and uveitis occurs. The implant is made of a material that dissolves over several months while gradually releasing the dexamethasone.
Active substance: dexamethasone
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